ISBN: 9783527608287
In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The auth… Mehr…
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Pharmacokinetics and Metabolism in Drug Design, Volume 31 (Methods and Principles in Medicinal Chemistry) - neues Buch
2006, ISBN: 9783527608287
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2006, ISBN: 9783527608287
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2006, ISBN: 9783527608287
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ISBN: 9783527608287
In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The auth… Mehr…
Smith, Dennis A. Van De Waterbeemd, Han, Walker, Don K. Mannhold, Raimund, Kubinyi, Hugo:
Pharmacokinetics and Metabolism in Drug Design, Volume 31 (Methods and Principles in Medicinal Chemistry) - neues Buch2006, ISBN: 9783527608287
Vch Pub, Digital Download, Auflage: 2, 207 Seiten, Publiziert: 2006-11-10T00:00:01Z, Produktgruppe: Digital Book Service, Pharmacology, Other Branches of Medicine, Medical & Healthcare Pr… Mehr…
2006
ISBN: 9783527608287
eBooks, eBook Download (PDF), Auflage, [PU: Wiley-VCH], [ED: 1], Wiley-VCH, 2006
2006, ISBN: 9783527608287
eBooks, eBook Download (PDF), 2. Auflage, [PU: Wiley-VCH], Wiley-VCH, 2006
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Detailangaben zum Buch - Pharmacokinetics and Metabolism in Drug Design
EAN (ISBN-13): 9783527608287
ISBN (ISBN-10): 3527608281
Erscheinungsjahr: 2006
Herausgeber: Wiley-VCH
207 Seiten
Sprache: eng/Englisch
Buch in der Datenbank seit 2007-11-13T23:51:45+01:00 (Zurich)
Detailseite zuletzt geändert am 2023-12-06T21:08:18+01:00 (Zurich)
ISBN/EAN: 3527608281
ISBN - alternative Schreibweisen:
3-527-60828-1, 978-3-527-60828-7
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: kubin, han, walker nor, hugo kubinyi, gerd folkers, guillaume, smith dennis, don smith
Titel des Buches: design doing
Daten vom Verlag:
Autor/in: Dennis A. Smith; Han van de Waterbeemd; Don K. Walker
Titel: Methods and Principles in Medicinal Chemistry; Pharmacokinetics and Metabolism in Drug Design
Verlag: Wiley-VCH; Wiley-VCH
187 Seiten
Erscheinungsjahr: 2006-08-21
Sprache: Englisch
111,99 € (DE)
111,99 € (AT)
Available
EA; E107; E-Book; Nonbooks, PBS / Chemie; Medizinische Chemie, Pharmazeutische Chemie; Verstehen; Arzneimitteldesign; Basic Pharmacology; Chemie; Chemistry; Drug Discovery & Development; Grundlagen der Pharmakologie; Medical Science; Medizin; Molecular Pharmacology; Molekulare Pharmakologie; Pharmakokinetik; Wirkstoffforschung u. -entwicklung; Wirkstoffforschung u. -entwicklung; Molekulare Pharmakologie; Grundlagen der Pharmakologie; BB
An understanding of pharmacokinetics is necessary to ensure that drugs that are active in vitro will also be active in the human body. The optimization of the pharmacokinetic properties of lead compounds is therefore of central importance to drug development. In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. They cover everything from the fundamental principles right up to the impact of pharmacokinetic parameters on the discovery of new drugs. From the contents: * Physicochemistry * Pharmacokinetics * Absorption * Distribution * Clearance * Renal Clearance * Metabolic (Hepatic) Clearance * Toxicity * Inter-Species Scaling * High(er) Throughput ADME Studies While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the clear and accessible style makes this book equally suitable for teaching students of pharmacy and related subjects, especially for those who feel that pharmacokinetics is covered too briefly in the standard textbooks.Weitere, andere Bücher, die diesem Buch sehr ähnlich sein könnten:
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