Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family.It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimic… Mehr…
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family.It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities.Lactoferrin has been shown to regulate the growth and differentiation of many types of cells. The results of recent studies indicate that lactoferrin is a potent regulator of dermal fibroblasts, and promotes cutaneous wound healing. The collagen gel contraction, a model of wound contraction during wound healing process, and migration of human fibroblasts were enhanced by lactoferrin.LRP-1 (LDL Receptor related Protein-1) acts as a signaling receptor for lactoferrin that mediate fibroblast response to lactoferrin by activating ERK/MAPK signaling pathway. In addition, lactoferrin promotes biosynthesis of extracellular matrix (ECM) component such as type-I collagen and hyaluronan.Hyaluronan is a major component of ECM in connective tissue and promotes wound healing.The promoting effect of lactoferrin on hyaluronan production was accompanied by promotion of HAS2 (hyaluronan synthase 2) expression.These observations suggest that lactoferrin promotes the wound healing by providing an ECM that promotes fibroblast migration. Lactoferrin is also known for its anti-inflammatory and immune modulating properties.According to recent in vivo study, lactoferrin promotes wound repair by promoting the early inflammatory phase of wound healing.Based on this, recombinant human lactoferrin was subsequently tested clinically in a Phase II trial in patients with diabetic ulcers and was found to be effective.Lactoferrin should be further evaluated in patients with diabetic and other types of ulcers.; PDF; Scientific, Technical and Medical > Medicine: general issues > Medical equipment & techniques > Medi, Springer Netherlands<
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Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimi… Mehr…
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities. Lactoferrin has been shown to regulate the growth and differentiation of many types of cells. The results of recent studies indicate that lactoferrin is a potent regulator of dermal fibroblasts, and promotes cutaneous wound healing. The collagen gel contraction, a model of wound contraction during wound healing process, and migration of human fibroblasts were enhanced by lactoferrin. LRP-1 (LDL Receptor related Protein-1) acts as a signaling receptor for lactoferrin that mediate fibroblast response to lactoferrin by activating ERK/MAPK signaling pathway. In addition, lactoferrin promotes biosynthesis of extracellular matrix (ECM) component such as type-I collagen and hyaluronan. Hyaluronan is a major component of ECM in connective tissue and promotes wound healing. The promoting effect of lactoferrin on hyaluronan production was accompanied by promotion of HAS2 (hyaluronan synthase 2) expression. These observations suggest that lactoferrin promotes the wound healing by providing an ECM that promotes fibroblast migration. Lactoferrin is also known for its anti-inflammatory and immune modulating properties. According to recent in vivo study, lactoferrin promotes wound repair by promoting the early inflammatory phase of wound healing. Based on this, recombinant human lactoferrin was subsequently tested clinically in a Phase II trial in patients with diabetic ulcers and was found to be effective. Lactoferrin should be further evaluated in patients with diabetic and other types of ulcers. Books > Biomedicine eBook, Springer Shop<
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(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimi… Mehr…
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities. Lactoferrin has been shown Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities. Lactoferrin has been shown Baby & Toddler > Baby Health > Baby Health & Grooming Kits, Springer<
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family.It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimic… Mehr…
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family.It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities.Lactoferrin has been shown to regulate the growth and differentiation of many types of cells. The results of recent studies indicate that lactoferrin is a potent regulator of dermal fibroblasts, and promotes cutaneous wound healing. The collagen gel contraction, a model of wound contraction during wound healing process, and migration of human fibroblasts were enhanced by lactoferrin.LRP-1 (LDL Receptor related Protein-1) acts as a signaling receptor for lactoferrin that mediate fibroblast response to lactoferrin by activating ERK/MAPK signaling pathway. In addition, lactoferrin promotes biosynthesis of extracellular matrix (ECM) component such as type-I collagen and hyaluronan.Hyaluronan is a major component of ECM in connective tissue and promotes wound healing.The promoting effect of lactoferrin on hyaluronan production was accompanied by promotion of HAS2 (hyaluronan synthase 2) expression.These observations suggest that lactoferrin promotes the wound healing by providing an ECM that promotes fibroblast migration. Lactoferrin is also known for its anti-inflammatory and immune modulating properties.According to recent in vivo study, lactoferrin promotes wound repair by promoting the early inflammatory phase of wound healing.Based on this, recombinant human lactoferrin was subsequently tested clinically in a Phase II trial in patients with diabetic ulcers and was found to be effective.Lactoferrin should be further evaluated in patients with diabetic and other types of ulcers.; PDF; Scientific, Technical and Medical > Medicine: general issues > Medical equipment & techniques > Medi, Springer Netherlands<
No. 9789400724679. Versandkosten:Instock, Despatched same working day before 3pm, zzgl. Versandkosten.
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimi… Mehr…
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities. Lactoferrin has been shown to regulate the growth and differentiation of many types of cells. The results of recent studies indicate that lactoferrin is a potent regulator of dermal fibroblasts, and promotes cutaneous wound healing. The collagen gel contraction, a model of wound contraction during wound healing process, and migration of human fibroblasts were enhanced by lactoferrin. LRP-1 (LDL Receptor related Protein-1) acts as a signaling receptor for lactoferrin that mediate fibroblast response to lactoferrin by activating ERK/MAPK signaling pathway. In addition, lactoferrin promotes biosynthesis of extracellular matrix (ECM) component such as type-I collagen and hyaluronan. Hyaluronan is a major component of ECM in connective tissue and promotes wound healing. The promoting effect of lactoferrin on hyaluronan production was accompanied by promotion of HAS2 (hyaluronan synthase 2) expression. These observations suggest that lactoferrin promotes the wound healing by providing an ECM that promotes fibroblast migration. Lactoferrin is also known for its anti-inflammatory and immune modulating properties. According to recent in vivo study, lactoferrin promotes wound repair by promoting the early inflammatory phase of wound healing. Based on this, recombinant human lactoferrin was subsequently tested clinically in a Phase II trial in patients with diabetic ulcers and was found to be effective. Lactoferrin should be further evaluated in patients with diabetic and other types of ulcers. Books > Biomedicine eBook, Springer Shop<
new in stock CH:::0.00 EUR. Versandkosten:zzgl. Versandkosten.
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimi… Mehr…
Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities. Lactoferrin has been shown Lactoferrin is an iron-binding glycoprotein belonging to the transferrin family. It acts as a defense in host animals against microbes and viruses, since it has a broad spectrum of antimicrobial and antiviral activities. Lactoferrin has been shown Baby & Toddler > Baby Health > Baby Health & Grooming Kits, Springer<
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Buch in der Datenbank seit 2012-05-01T10:20:21+02:00 (Zurich) Detailseite zuletzt geändert am 2023-01-05T18:17:19+01:00 (Zurich) ISBN/EAN: 9400724675
ISBN - alternative Schreibweisen: 94-007-2467-5, 978-94-007-2467-9 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: takayama, yoshiharu
Daten vom Verlag:
Autor/in: Yoshiharu Takayama Titel: Lactoferrin and its Role in Wound Healing Verlag: Springer; Springer Netherland 108 Seiten Erscheinungsjahr: 2011-10-25 Dordrecht; NL Sprache: Englisch 96,29 € (DE) 99,00 € (AT) 118,00 CHF (CH) Available XII, 108 p.
EA; E107; eBook; Nonbooks, PBS / Medizin/Nichtklinische Fächer; Medizinische Forschung; Verstehen; Granulation tissue; Hyaluronan; Lactoferrin; Reepithelialization; Wound Healing; Receptors; C; Biomedical Research; Human Physiology; Cell Biology; Protein Biochemistry; Proteins; Membrane Trafficking; Biomedical and Life Sciences; Physiologie; Zellbiologie (Zytologie); Biochemie; BB
“Lactoferrin and its Role in Wound Healing” summarizes the recent advances of molecular mechanisms of wound healing. It is a complex physiological process that requires the regulation of different types of cells such as immune cells, keratinocytes, fibroblasts, and endothelial cells.Lactoferrin was first identified as an iron-binding glycoprotein abundantly found in milk. It has been considered to play important roles in host defense, since lactoferrin shows broad spectrum of anti-bacterial and anti-viral activities, arising from its iron-chelating property. Furthermore, lactoferrin can regulate the function of innate and adaptive immune cells and exhibits immuno-modulating properties. These activities of lactoferrin implicate that potential use of lactoferrin as a wound healing agent. In addition, this book shows that lactoferrin is a potent regulator of dermal fibroblasts and epidermal keratinocytes, and promotes skin or corneal epithelial wound healing by increasing their proliferation, migration or deposition of extracellular matrix (ECM) components such as collagen and hyaluronan. This book provides the scientific background on use of lactoferrin as a wound healing agent. Indeed, lactoferrin exerts its biological effects by binding to specific lactoferrin receptors on target cells. This book also covers the in-depth information on roles of lactoferrin as a signaling molecule. Provides the recent advances in molecular mechanisms of wound healing Provides in-depth information on roles of lactoferrin as a signaling molecule Presents the scientific background on use of lactoferrin as a wound healing agent
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